On the Effects of a Chronic Deoxynivalenol Intoxication on Performance, Haematological and Serum Parameters of Pigs when Diets are Offered Either for Ad Libitum Consumption or Fed Restrictively
- 22 July 2005
- journal article
- Published by Wiley in Journal of Veterinary Medicine Series A
- Vol. 52 (6), 305-314
- https://doi.org/10.1111/j.1439-0442.2005.00734.x
Abstract
Wheat infected naturally with Fusarium, contaminated mainly with deoxynivalenol (DON) (16.6 mg DON/kg), was added to a total constant wheat content of 400 g/kg diet. To distinguish between differences in feed intake and specific effects of the DON contaminated diet, control and DON contaminated feed was administered for 11 weeks under ad libitum and restrictive feeding conditions to 48 pigs of both sexes, which were randomly divided into four groups (n = 12 per group). Feed intake was 2.90 kg/day, live weight gain 987 g/day and feed to gain ratio 2.77 kg/kg for the ad libitum fed control group. The group fed DON contaminated wheat ad libitum significantly consumed 15% less feed and gained 13% less live weight, while the feed to gain ratio was unaffected. Moreover, it was concluded that the lower growth performance by DON contaminated feed resulted mainly from the lower voluntary feed intake, because there were no differences in live weight gain between the groups with the restrictive feeding regimen. On the contrary, metabolizable energy, nitrogen retention digestibility of organic matter, crude protein, crude fat and crude fibre were significantly increased by 3, 10, 3, 6, 9 and 20% in the DON group respectively. Animals fed DON contaminated diets needed more time to consume the restrictive ration than the control group. For example in the first hour after feeding 85% of the control pigs had consumed all feed, but only 39% of the DON group had. There were only few differences in haematological and serum parameters, which were characterized by a high variation between individuals. DON and IgA concentrations in serum were significantly influenced by DON exposure.Keywords
This publication has 31 references indexed in Scilit:
- Analysis of deoxynivalenol and de-epoxy-deoxynivalenol in animal tissues by liquid chromatography after clean-up with an immunoaffinity columnMycotoxin Research, 2003
- Effects of Diets with Graded Levels of Naturally Deoxynivalenol‐contaminated Oats on Immune Response in Growing PigsJournal of Veterinary Medicine Series A, 1997
- Invited Review: TOXICOLOGY OF DEOXYNIVALENOL (VOMITOXIN)Journal of Toxicology and Environmental Health, 1996
- Vomitoxin (deoxynivalenol)-induced IgA nephropathy in the B6C3F1 mouse: dose response and male predilectionToxicology, 1994
- Role of gender and strain in vomitoxin‐induced dysregulation of IgA production and IgA nephropathy in the mouseJournal of Toxicology and Environmental Health, 1994
- Influence of Low-Level Exposure to Fusarium Mycotoxins on Selected Immunological and Hematological Parameters in Young SwineFundamental and Applied Toxicology, 1994
- The effects of naturally deoxynivalenol-contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigsVeterinary Research Communications, 1993
- A preliminary examination of potential interactions between deoxynivalenol (DON) and other selected Fusarium metabolites in growing pigsCanadian Journal of Animal Science, 1992
- EFFECT OF DEOXYNIVALENOL (DON)-CONTAMINATED DIET FED TO GROWING-FINISHING PIGS ON THEIR PERFORMANCE AT MARKET WEIGHT, NITROGEN RETENTION AND DON EXCRETIONCanadian Journal of Animal Science, 1986
- THE SIGNIFICANCE OF THE REDUCED FEED CONSUMPTION OBSERVED IN GROWING PIGS FED VOMITOXIN-CONTAMINATED DIETSCanadian Journal of Animal Science, 1986