Early stage biliary and intrahepatic migration of Opisthorchis viverrini in the golden hamster
- 1 March 2007
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of Helminthology
- Vol. 81 (1), 39-41
- https://doi.org/10.1017/s0022149x07212106
Abstract
In Thailand, infection with the liver fluke Opisthorchis viverrini is a serious health problem, with over 8.6 million human infections each year. Early stage biliary intrahepatic migration and infection of O. viverrini in the Syrian golden hamster were used to study the growth and development of this fluke. Fifty metacercariae of O. viverrini were introduced into each hamster by gastric intubation. Worms were found to migrate rapidly from the stomach to the gall bladder and hepatic duct, where they remained in relatively constant numbers until the end of week 8. Sexual development of worms was rapid, with full development of the uterus and testes by one and one half weeks and the appearance of eggs in the uterus by the beginning of the third week of infection. Worm growth as indicated by body length had ceased by week 8. Hamsters demonstrated development of a full reproductive cycle with in three to four weeks, and this generation continued until 8 weeks.Keywords
This publication has 8 references indexed in Scilit:
- Localisation of parasite antigens and inflammatory responses in experimental opisthorchiasisInternational Journal for Parasitology, 2000
- Opisthorchis viverrini: Changes of the tegumental surface in newly excysted juvenile, first-week and adult flukesInternational Journal for Parasitology, 1993
- Turnover of biliary epithelial cells in Clonorchis sinensis infected ratsThe Korean Journal of Parasitology, 1993
- Quantitative post-mortem study of Opisthorchis viverrini in man in north-east ThailandTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
- Incidence of Endemic Opisthorchis Viverrini Infection in a Village in Northeast ThailandThe American Journal of Tropical Medicine and Hygiene, 1985
- Opisthorchis viverrini: the relationship between egg production, worm size and intensity of infection in the hamsterTransactions of the Royal Society of Tropical Medicine and Hygiene, 1983
- Clonorchis and ClonorchiasisAdvances in Parasitology, 1967
- STUDIES ON OPISTHORCHIS VIVERRINI IN THAILAND1American Journal of Epidemiology, 1955