Genetic and metabolic aspects of androstenone and skatole deposition in pig adipose tissue: A review(Open Access publication)
Open Access
- 21 December 2007
- journal article
- review article
- Published by Springer Science and Business Media LLC in Genetics Selection Evolution
- Vol. 40 (1), 129-143
- https://doi.org/10.1051/gse:2007040
Abstract
High levels of androstenone and skatole in fat tissues are considered the primary causes of boar taint, an unpleasant odour and flavour of the meat from non-castrated male pigs. The aim of this article is to review our current knowledge of the biology and genetic control of the accumulation of androstenone and skatole in fat tissue. Two QTL mapping studies have shown the complexity of the genetic control of these traits. During the last ten years, several authors have taken a more physiological approach to investigate the involvement of genes controlling the metabolism of androstenone and skatole. Although some authors have claimed the identification of candidate genes, it is more appropriate to talk about target genes. This suggests that genes affecting androstenone and skatole levels will have to be sought for among specific or non-specific transcription factors interacting with these target geneThis publication has 42 references indexed in Scilit:
- Breed-associated variations in the sequence of the pig 3β-hydroxysteroid dehydrogenase gene1Journal of Animal Science, 2007
- Detection of quantitative trait loci for androstenone, skatole and boar taint in a cross between Large White and Meishan pigsAnimal Genetics, 2004
- Characterisation of androstenone metabolism in pig liver microsomesChemico-Biological Interactions, 2004
- Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1α)-deficient miceBiochemical Pharmacology, 2003
- Support for single major genes influencing fat androstenone level and development of bulbo-urethral glands in young boarsGenetics Selection Evolution, 1997
- Physiological aspects of androstenone and skatole formation in the boar—A review with experimental dataMeat Science, 1994
- Steroid Hormone Pathways in the Pig, with Special Emphasis on Boar Odor: A ReviewJournal of Animal Science, 1986
- Biosynthesis of androgens and pheromonal steroids in neonatal porcine testicular preparationsFEBS Letters, 1985
- 16-Unsaturated C19 steroids a review of their chemistry, biochemistry and possible physiological roleJournal of Steroid Biochemistry, 1972
- The biosynthesis of androst-16-enes in boar testis tissueBiochemical Journal, 1970