Changing epidemiology and clinical issues arising in an ageing cystic fibrosis population
- 15 November 2010
- journal article
- review article
- Published by SAGE Publications in Therapeutic Advances in Respiratory Disease
- Vol. 5 (2), 105-119
- https://doi.org/10.1177/1753465810386051
Abstract
Improvements in the quality and implementation of medical care for individuals with cystic fibrosis (CF) have resulted in a dramatic improvement in survival. Many of these strategies have focused on the effective management of pulmonary disease which has delayed its manifestations into later years. With an increasing number of patients surviving to later years the impact of chronic inflammation and nutritional compromise on other organ systems over a lifetime are increasingly manifest. This review highlights the changing epidemiology of the ageing CF population and the complications that may ensue.Keywords
This publication has 95 references indexed in Scilit:
- Diabetes as a Determinant of Mortality in Cystic FibrosisDiabetes Care, 2009
- High treatment burden in adults with cystic fibrosis: Challenges to disease self-managementJournal of Cystic Fibrosis, 2009
- Genetic Determinants and Epidemiology of Cystic Fibrosis–Related DiabetesDiabetes Care, 2008
- Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus ReportThe Journal of Pediatrics, 2008
- Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practiceJournal of Cystic Fibrosis, 2008
- Exacerbations in cystic fibrosis: 2 {middle dot} PreventionThorax, 2007
- Risk of pancreatic cancer in patients with cystic fibrosisGut, 2007
- Epidemiology of cystic fibrosis-related diabetesThe Journal of Pediatrics, 2005
- Cancer risk among patients with cystic fibrosisThe Journal of Pediatrics, 1991
- Improved respiratory prognosis in patients with cystic fibrosis with normal fat absorptionThe Journal of Pediatrics, 1982