A New Access Route to Functionalized Cispentacins from Norbornene β-Amino Acids
- 19 December 2012
- journal article
- research article
- Published by Wiley in Chemistry – A European Journal
- Vol. 19 (6), 2102-2107
- https://doi.org/10.1002/chem.201203183
Abstract
An efficient and simple new stereocontrolled access route to novel disubstituted cispentacin derivatives with multiple stereogenic centers from norbornene β-lactam has been developed. The synthesis involves olefinic bond functionalization by dihydroxylation followed by oxidative ring cleavage and transformation of the dialdehyde intermediate through a Wittig reaction.This publication has 101 references indexed in Scilit:
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