Direct measurement of Raman spectra of intact lens in a whole eyeball

Abstract
The Raman spectrum of an intact rabbit and rat lens was measured intraocularly. The Raman spectrum was identical to that of an excised lens. There was no evidence for Raman bands from cornea, aqueous humor, or other ocular tissue in the specturm of intact lens in the eyeball. The result is an important step toward the clinical application of Raman spectroscopy in the field of [human] cataract research.