Neurological Outcome After Out-of-Hospital Cardiac Arrest
- 1 July 1989
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 46 (7), 753-756
- https://doi.org/10.1001/archneur.1989.00520430047015
Abstract
• The prognostic value of cerebrospinal fluid (CSF) and serum neuron-specific enolase and brain-type creatine kinase isozyme (CK-BB) measurements was studied in 75 consecutive victims of out-of-hospital cardiac arrest. All patients with a CSF neuron-specific enolase level of more than 24 ng/ml 24 hours after cardiac arrest remained unconscious and died. The CSF CK-BB level was as reliable as an index of brain injury.Cerebrospinal fluid neuron-specific enolase, CSF CK-BB and serum neuron-specific enolase levels correlated with the neurological outcome at 3 months. Thus, the analysis of these enzymes in CSF seems to be useful in the early prognostic assessment of cardiac arrest victims.Keywords
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