Increased Frequency of HL‐A8 in Sjogren's Syndrome
- 1 October 1975
- journal article
- Published by Wiley in Tissue Antigens
- Vol. 6 (4), 342-346
- https://doi.org/10.1111/j.1399-0039.1975.tb00653.x
Abstract
The histocompatibility antigen, HL‐A8, was found to be elevated in patients with Sjogren's syndrome. Among 24 patients, the frequency of HL‐A8 was 58% compared to 21% among controls (P < 0.001 after correction). With the addition of this disorder to the list of other autoimmune diseases associated with HL‐A8, it now seems possible to postulate a single basis autoimmune defect gene in high linkage disequilibrium with HL‐A8.Keywords
This publication has 21 references indexed in Scilit:
- HL-A ANTIGENS AND DIABETES MELLITUSThe Lancet, 1974
- HL-A AND IDIOPATHIC ADDISON'S DISEASEThe Lancet, 1974
- HL-A antigens and the sicca syndrome.Annals Of The Rheumatic Diseases, 1974
- HL-A ANTIGENS IN SARCOIDOSIS AND RHEUMATOID ARTHRITISThe Lancet, 1972
- "Sicca Complex" in Liver DiseaseBMJ, 1970
- THYROID AND GASTRIC AUTOIMMUNITY IN PATIENTS WITH DIABETES MELLITUSThe Lancet, 1970
- SEROTYPING FOR HOMOTRANSPLANTATION XVIII. REFINEMENT OF MICRODROPLET LYMPHOCYTE CYTOTOXICITY TESTTransplantation, 1968
- FURTHER STUDIES ON THE SPECIFICITY OF PRESUMED IMMUNE ASSOCIATIONS OF MYASTHENIA GRAVIS AND CONSIDERATION OF POSSIBLE PATHOGENIC IMPLICATIONSAnnals of the New York Academy of Sciences, 1966
- MYASTHENIA GRAVIS AS AN AUTOIMMUNE DISEASE: CLINICAL ASPECTSAnnals of the New York Academy of Sciences, 1966
- SJÖGRENʼS SYNDROMEMedicine, 1965