Antibody production suppressed in the domestic fowl(gallus domesticus)by zinc deficiency
Open Access
- 1 January 1983
- journal article
- research article
- Published by Informa UK Limited in Avian Pathology
- Vol. 12 (1), 141-146
- https://doi.org/10.1080/03079458308436156
Abstract
Fowls maintained on a zinc‐deficient diet from hatching and immunised either by intraperitoneal injections of bovine serum albumin (BSA) or by a combination of ocular drops and intraperitoneal injections showed no antibody response as judged by immunoelectrophoresis and immuno‐fluorescence, whereas birds on a zinc‐sufficient diet had serum antibody and anti‐BSA cells in the Harderian gland, Peyer's patches, spleen and thymus. The localisation of immunoglobulins did npt differ between control and deficient birds except in the bursa of Fabricius where follicle‐associated epithelium of deficient fowls stained for immunoglobulins, especially IgA, whereas in sections from control birds these cells remained unstained.Keywords
This publication has 10 references indexed in Scilit:
- Severe Zinc Deficiency in Humans: Association with a Reversible T-Lymphocyte DysfunctionAnnals of Internal Medicine, 1981
- Immunoelectrophoresis employing avian antiseria for the detection and quantitation of Pasteurella multocida antigensJournal of Immunological Methods, 1981
- Nutrition and immunityJournal of Clinical Immunology, 1981
- Monocytosis in experimental zinc deficiency of domestic birdsAvian Pathology, 1980
- Some histochemical observations on zinc deficiency in chickensAvian Pathology, 1979
- The Effect of Restricted Dietary Intake on the Antibody Mediated Response of the Zinc Deficient A/J MouseJournal of Nutrition, 1978
- Effect of Zinc Deficiency on the Immune Response of the Young Adult A/J MouseJournal of Nutrition, 1977
- Peyer's Patches: Lack of Specific Antibody-Containing Cells after Oral and Parenteral ImmunizationPublished by The American Association of Immunologists ,1971
- A PARAFFIN EMBEDDING TECHNIQUE FOR STUDIES EMPLOYING IMMUNOFLUORESCENCEJournal of Histochemistry & Cytochemistry, 1962
- STUDIES ON ANTIBODY PRODUCTIONThe Journal of Experimental Medicine, 1955