Interactions among Cells of the Developing Neural Retinain vitro1

Abstract
Two models are presented for mechanisms leading to the formation of layers during the development of the chick neural retina. The first proposes that the different cells possessintrinsic characteristics that allow them to self sort into specific patterns. The second suggests that the cells migrate, or are moved, along a substrate which guides them into specific locations. Supporting evidence is presented for both hypotheses, suggesting that the overall process is highly complex, using elements of each mechanism.