Comment on ‘Clinical and histological characterization of vesicular COVID‐19 rashes: a prospective study in a tertiary care hospital’. Pseudoherpetic Grover disease seems to occur in patients with COVID‐19 infection
- 21 May 2020
- journal article
- letter
- Published by Oxford University Press (OUP) in Clinical and Experimental Dermatology
- Vol. 45 (7), 896-898
- https://doi.org/10.1111/ced.14305
Abstract
We have read with great interest the article by Fernandez‐Nieto et al. showing histopathological pictures of one of the two biopsied cases from their 24 patients diagnosed of vesicular lesions related to COVID‐19.1 They additionally performed a real‐time PCR for SARS‐CoV‐2 that was negative in four tested cases.1 Regarding their case histopathological pictures, we agree with their description as we can observe acantholytic cells, some of them with dyskeratotic features or grouped without a clear molding of nucleus but reminiscent of the multinucleated giant cells typically observed in herpetic lesions, a picture that looks to our eyes, most likely as an infrequent entity named pseudoherpetic Grover disease (GD),2 first described as vesicular GD by Fernandez‐Figueras.3Keywords
This publication has 5 references indexed in Scilit:
- Clinical and histological characterization of vesicular COVID‐19 rashes: a prospective study in a tertiary care hospitalClinical and Experimental Dermatology, 2020
- Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 casesBritish Journal of Dermatology, 2020
- Hailey–Hailey Disease With Coexistent Herpes Virus Infection: Insights Into the Diagnostic Conundrum of Herpetic/Pseudoherpetic Features in Cutaneous Acantholytic DisordersThe American Journal of Dermatopathology, 2018
- Clinico-Pathological Study of 4 Cases of Pseudoherpetic Grover Disease: The Same as Vesicular Grover DiseaseThe American Journal of Dermatopathology, 2018
- Grover Disease: A Reappraisal of Histopathological Diagnostic Criteria in 120 CasesThe American Journal of Dermatopathology, 2010