Association of PHF11 polymorphisms with asthma and allergy
Open Access
- 1 July 2010
- Vol. 65 (7), 659-660
- https://doi.org/10.1136/thx.2009.124511
Abstract
Two recent reports in Thorax failed to show an association between polymorphisms within PHF11 and asthma phenotypes.1 2 Against this, there is evidence for an association between PHF11 and one or more phenotypes of total immunoglobulin E (IgE), atopic eczema and asthma in six independent cohorts.3–5 Here, we argue in support of the continued investigation into the biological role of PHF11 in the unravelling of the pathogenesis of atopic disease and asthma. In the report by …Keywords
This publication has 5 references indexed in Scilit:
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- Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitisGenes & Immunity, 2005
- Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthmaNature Genetics, 2003