Antiproliferative Xanthones of Terminalia calcicola from the Madagascar Rain Forest
- 27 February 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 70 (4), 679-681
- https://doi.org/10.1021/np060627g
Abstract
A bioassay-guided fractionation of the EtOH extract of the Madagascan plant Terminalia calcicola led to the isolation of two new cytotoxic xanthones, termicalcicolanone A (1) and termicalcicolanone B (2). The structures of the new compounds were established on the basis of one- and two-dimensional NMR spectroscopic data. Both compounds showed modest antiproliferative activity toward the A2780 human ovarian cancer cell line.Keywords
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