Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein
Open Access
- 1 July 2003
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 278 (27), 24294-24301
- https://doi.org/10.1074/jbc.m211161200
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Distinct Mechanisms by Mutant Presenilin 1 and 2 Leading to Increased Intracellular Levels of Amyloid β-Protein 42 in Chinese Hamster Ovary CellsBiochemistry, 2003
- Presenilin-dependent Intramembrane Proteolysis of CD44 Leads to the Liberation of Its Intracellular Domain and the Secretion of an Aβ-like PeptideJournal of Biological Chemistry, 2002
- Presenilin 1 Mutations Activate γ42-Secretase but Reciprocally Inhibit ε-Secretase Cleavage of Amyloid Precursor Protein (APP) and S3-Cleavage of NotchJournal of Biological Chemistry, 2002
- Distinct Intramembrane Cleavage of the β-Amyloid Precursor Protein Family Resembling γ-Secretase-like Cleavage of NotchJournal of Biological Chemistry, 2001
- Biochemical Characterization of the γ-Secretase Activity That Produces β-Amyloid PeptidesBiochemistry, 2001
- Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased Aβ42 secretion in mammalian cells but impaired Notch/lin-I2 signalling in C. elegansNeuroReport, 2000
- Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-ProteinNeurobiology of Disease, 1998
- Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)Neuron, 1994
- Amyloid β-peptide is produced by cultured cells during normal metabolismNature, 1992
- Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's diseaseJournal of Molecular Biology, 1991