Risk of recurrent spontaneous preterm birth: a systematic review and meta-analysis
Open Access
- 1 June 2017
- Vol. 7 (6), e015402
- https://doi.org/10.1136/bmjopen-2016-015402
Abstract
Objective To determine the risk of recurrent spontaneous preterm birth (sPTB) following sPTB in singleton pregnancies. Design Systematic review and meta-analysis using random effects models. Data sources An electronic literature search was conducted in OVID Medline (1948–2017), Embase (1980–2017) and ClinicalTrials.gov (completed studies effective 2017), supplemented by hand-searching bibliographies of included studies, to find all studies with original data concerning recurrent sPTB. Study eligibility criteria Studies had to include women with at least one spontaneous preterm singleton live birth (Results Overall, 32 articles involving 55 197 women, met all inclusion criteria. Generally studies were well conducted and had a low risk of bias. The absolute risk of recurrent sPTB at Conclusions The risk of recurrent sPTB is high and is influenced by the underlying clinical pathway leading to the birth. This information is important for clinicians when discussing the recurrence risk of sPTB with their patients.Funding Information
- Canadian Institutes of Health Research
- Alberta Children's Hospital Research Institute
This publication has 52 references indexed in Scilit:
- Does the clinical presentation of a prior preterm birth predict risk in a subsequent pregnancy?American Journal of Obstetrics and Gynecology, 2015
- The NICHD Consecutive Pregnancies Study: recurrent preterm delivery by subtypeAmerican Journal of Obstetrics and Gynecology, 2013
- Subtypes of Preterm Birth and the Risk of Postneonatal DeathThe Journal of Pediatrics, 2013
- Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000The Lancet, 2012
- A Randomized Trial of Micronized Progesterone for the Prevention of Recurrent Preterm BirthAmerican Journal of Perinatology, 2011
- CIHI Survey: Hospital Costs for Preterm and Small-for-Gestational Age Babies in CanadaWorld Health & Population, 2009
- Preterm birth prevention by 17 alpha-hydroxyprogesterone caproate vs. daily nursing surveillance.2009
- Neonatal outcome in preterm deliveries between 23 and 27 weeks’ gestation with and without preterm premature rupture of membranesArchiv für Gynäkologie, 2008
- Recurrent Preterm BirthSeminars in Perinatology, 2007
- The Impact of Interpregnancy Interval and Previous Preterm Birth on the Subsequent Risk of Preterm BirthJournal of the Society for Gynecologic Investigation, 2005