Mapping Adverse Drug Reactions in Chemical Space
- 20 April 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 52 (9), 3103-3107
- https://doi.org/10.1021/jm801546k
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Understanding False Positives in Reporter Gene Assays: in Silico Chemogenomics Approaches To Prioritize Cell-Based HTS DataJournal of Chemical Information and Modeling, 2007
- Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical StructureChemMedChem, 2007
- When good drugs go badNature, 2007
- Bridging Chemical and Biological Space: “Target Fishing” Using 2D and 3D Molecular DescriptorsJournal of Medicinal Chemistry, 2006
- Prediction of Biological Targets for Compounds Using Multiple-Category Bayesian Models Trained on Chemogenomics DatabasesJournal of Chemical Information and Modeling, 2006
- Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug developmentDrug Discovery Today, 2005
- Can the pharmaceutical industry reduce attrition rates?Nature Reviews Drug Discovery, 2004
- Withdrawal of cerivastatin from the world marketTrials, 2001
- Drug-Related Morbidity and MortalityArchives of Internal Medicine, 1995
- The Nature of Adverse Events in Hospitalized PatientsThe New England Journal of Medicine, 1991