Germline Mutations in Oncogene-Induced Senescence Pathways Are Associated With Multiple Sessile Serrated Adenomas
Open Access
- 1 February 2014
- journal article
- research article
- Published by Elsevier BV in Gastroenterology
- Vol. 146 (2), 520-529.e6
- https://doi.org/10.1053/j.gastro.2013.10.045
Abstract
No abstract availableThis publication has 66 references indexed in Scilit:
- A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic InterventionCancer Cell, 2013
- Pif1 family helicases suppress genome instability at G-quadruplex motifsNature, 2013
- Comprehensive molecular characterization of human colon and rectal cancerNature, 2012
- Cancer Risks for Relatives of Patients With Serrated PolyposisThe American Journal of Gastroenterology, 2012
- Prevalence of Different Subtypes of Serrated Polyps and Risk of Synchronous Advanced Colorectal Neoplasia in Average-Risk Population Undergoing First-Time ColonoscopyClinical and Translational Gastroenterology, 2012
- Up and downregulation of p16Ink4a expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancerLaboratory Investigation, 2011
- Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)Familial Cancer, 2010
- V600E Braf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16
INK4a
EMBO Molecular Medicine, 2010
- Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicineEMBO Molecular Medicine, 2010
- Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpointsNature, 2006