Biofilms
Top Cited Papers
Open Access
- 2 June 2010
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Cold Spring Harbor Perspectives in Biology
- Vol. 2 (7), a000398
- https://doi.org/10.1101/cshperspect.a000398
Abstract
The ability to form biofilms is a universal attribute of bacteria. Biofilms are multicellular communities held together by a self-produced extracellular matrix. The mechanisms that different bacteria employ to form biofilms vary, frequently depending on environmental conditions and specific strain attributes. In this review, we emphasize four well-studied model systems to give an overview of how several organisms form biofilms: Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. Using these bacteria as examples, we discuss the key features of biofilms as well as mechanisms by which extracellular signals trigger biofilm formation.Keywords
This publication has 81 references indexed in Scilit:
- Innate and Induced Resistance Mechanisms of Bacterial BiofilmsPublished by Springer Science and Business Media LLC ,2008
- Role of polysaccharides in Pseudomonas aeruginosa biofilm developmentCurrent Opinion in Microbiology, 2007
- Biofilm Formation by Plant-Associated BacteriaAnnual Review of Microbiology, 2007
- Development of intracellular bacterial communities of uropathogenicEscherichia colidepends on type 1 piliCellular Microbiology, 2007
- Antibiotics as signalling moleculesPhilosophical Transactions B, 2007
- Rethinking 'secondary' metabolism: physiological roles for phenazine antibioticsNature Chemical Biology, 2006
- Independent and Interchangeable Multimerization Domains of the AbrB, Abh, and SpoVT Global Regulatory ProteinsJournal of Bacteriology, 2005
- Aminoglycoside antibiotics induce bacterial biofilm formationNature, 2005
- Effect of Subinhibitory Antibiotic Concentrations on Polysaccharide Intercellular Adhesin Expression in Biofilm-Forming Staphylococcus epidermidisAntimicrobial Agents and Chemotherapy, 2000
- Impact of theagrQuorum‐Sensing System on Adherence to Polystyrene inStaphylococcus aureusThe Journal of Infectious Diseases, 2000