Seroprevalence and trend of hepatitides among blood donors in a district hospital in Ghana: a nine-year retrospective, descriptive cross-sectional study
- 22 October 2019
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Immunoassay and Immunochemistry
- Vol. 41 (1), 71-83
- https://doi.org/10.1080/15321819.2019.1682601
Abstract
Hepatitis infections are among the greatest threats to human existence and survival and hence poses a serious public health challenge in blood donation. This study aimed to determine the prevalence and trend of hepatitis infections among voluntary blood donors at Nkenkaasu District Hospital. A retrospective study of voluntary blood donors’ records from January 2010 to December 2018 was conducted. Data on the donors’ age, sex and serum HBsAg and Hepatitis C virus results were retrieved from the Laboratory’s register and analyzed with SPSS version 16.0. Out of the 3306 total donors, the seroprevalence of hepatitis C infection was 11.7% and hepatitis B infection was 10.3%. Only 1.4% of the donors were co-infected with both pathogens and 82.7% had no infection. Rhesus blood group had a significant association with Hepatitis B (P = 0.005). As at 2010, both hepatitis infections had the same prevalence (73), from 2011 to 2018 both showed inconsistent trends. The relatively high seroprevalence of hepatitis infections identified from the study poses a greater threat to blood safety. Extensive screening of blood donors using standard techniques is highly recommended to ensure that recipients receive safe blood.Keywords
This publication has 16 references indexed in Scilit:
- Transfusion-Transmissible Infections among Voluntary Blood Donors at Wolaita Sodo University Teaching Referral Hospital, South EthiopiaCanadian Journal of Infectious Diseases and Medical Microbiology, 2016
- The Prevalence of Transfusion Transmitted Infections in ABO Blood Groups and Rh Type SystemHematology Reports, 2014
- A 10 Years Comparative Study to Assess Trends in Seroprevalence of Transfusion Transmitted Infections among Blood Donors at Gwalior, IndiaOpen Journal of Blood Diseases, 2014
- Sero-Prevalence of Hepatitis B Virus Infection among Blood Donors: A Retrospective Study in the Kintampo Municipal Hospital, GhanaOpen Journal of Medical Microbiology, 2014
- ABO Research in the Modern Era of GenomicsTransfusion Medicine Reviews, 2012
- A Survey of prevalence of serum antibodies to human immunodeficiency deficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) among blood donorsNorth American Journal of Medical Sciences, 2011
- The functional importance of blood group‐active molecules in human red blood cellsVox Sanguinis, 2010
- A Genetic Variant of Hepatitis B Virus Divergent from Known Human and Ape Genotypes Isolated from a Japanese Patient and Provisionally Assigned to New Genotype JJournal of Virology, 2009
- Hepatitis C infection and the patient with end-stage renal diseaseHepatology, 2002
- Seroprevalence of anti HCV antibodies among blood donors in Kathmandu valley, NepalKathmandu University Medical Journal, 1970