Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease
- 30 April 2010
- journal article
- research article
- Published by Elsevier BV in The American Journal of Pathology
- Vol. 176 (4), 1600-1606
- https://doi.org/10.2353/ajpath.2010.090406
Abstract
No abstract availableKeywords
This publication has 70 references indexed in Scilit:
- Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s diseaseActa Neuropathologica, 2009
- Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same CoinThe Scientific World Journal, 2009
- Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathwayNeurobiology of Disease, 2008
- Proteinases as hormones: targets and mechanisms for proteolytic signalingBiological Chemistry, 2008
- Interleukin 8 is differently expressed and modulated by PAR‐1 activation in early and late endothelial progenitor cellsJournal of Cellular and Molecular Medicine, 2008
- Prothrombin/thrombin and the thrombin receptors PAR-1 and PAR-4 in the brain: Localization, expression and participation in neurodegenerative diseasesThrombosis and Haemostasis, 2008
- Bad for the Heart, Bad For the Mind?Science, 2001
- Identification of Thrombin Receptors in Rat Brain Capillary Endothelial CellsJournal of Cerebral Blood Flow & Metabolism, 2000
- Nitric Oxide Synthase Activity Is Elevated in Brain Microvessels in Alzheimer′s DiseaseBiochemical and Biophysical Research Communications, 1994
- Thrombin accumulation in brains of patients with Alzheimer's diseaseNeuroscience Letters, 1992