Malignant Liver Tumors Treated with MR Imaging–guided Laser-induced Thermotherapy: Experience with Complications in 899 Patients (2,520 lesions)
- 1 November 2002
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 225 (2), 367-377
- https://doi.org/10.1148/radiol.2252011171
Abstract
PURPOSE: To evaluate the complications from laser-induced thermotherapy (LITT) of malignant liver tumors and demonstrate that LITT is safe as an outpatient procedure. MATERIALS AND METHODS: During 8 years, 899 patients with malignant liver tumors were treated with magnetic resonance (MR) imaging–guided LITT. A total of 2,132 LITT procedures were performed to treat 2,520 lesions. To account for the technical evolution of LITT during this time and the change from performing the procedure on an inpatient basis to performing it on an outpatient basis, patients were assigned to four groups. Overall complication rates and major and minor complications in the inpatient versus outpatient groups were evaluated. Multidimensional contingency table analysis with the χ2 test was performed. RESULTS: On the basis of a total of 2,132 LITT procedures performed, complications were divided into major and minor categories and detected at clinical or imaging studies. Major complications included three deaths (0.1%) within 30 days after LITT, pleural effusion requiring thoracentesis in 16 (0.8%) cases, hepatic abscess requiring drainage in 15 (0.7%) cases, bile duct injury in four (0.2%) cases, segmental infarction in three (0.1%) cases, and hemorrhage requiring transfusion in one (0.05%) case. Minor complications included postprocedural fever in 710 (33.3%), pleural effusion not requiring thoracentesis in 155 (7.3%), subcapsular hematoma in 69 (3.2%), subcutaneous hematoma in 24 (1.1%), pneumothorax in seven (0.3%), and hemorrhage in two (0.1%) cases. Outpatient management did not significantly affect pleural effusion (P = .96) or subcapsular hematoma (P = .33) rate. CONCLUSION: MR imaging–guided LITT with local anesthesia is safe and yields an acceptably low rate of major complications. © RSNA, 2002This publication has 40 references indexed in Scilit:
- Hepatocellular Carcinoma: Long-term Results of Combined Treatment with Laser Thermal Ablation and Transcatheter Arterial ChemoembolizationRadiology, 2001
- Survival after percutaneous, image-guided, thermal ablation of hepatic metastases from colorectal cancerDiseases of the Colon & Rectum, 2000
- Laserinduzierte Thermotherapie (LITT) von Lebermetastasen in einem offenen 0,2 T MRT∗RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2000
- Perkutane interstitielle Thermotherapie maligner LebertumorenRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2000
- Internally cooled power laser for MR-guided interstitial laser-induced thermotherapy of liver lesions: initial clinical results.Radiology, 1998
- Radio-frequency thermal ablation of liver metastases with a cooled-tip electrode needle: results of a pilot clinical trialEuropean Radiology, 1998
- Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes.Radiology, 1997
- Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy: technique and prospective results.Radiology, 1995
- Interstitial laser photocoagulation as treatment for breast cancerBritish Journal of Surgery, 1995
- Interstitial hyperthermia of colorectal liver metastases with a US-guided Nd-YAG laser with a diffuser tip: a pilot clinical study.Radiology, 1993