2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest
- 1 April 2019
- journal article
- research article
- Published by Human Kinetics in Journal of Aging and Physical Activity
- Vol. 27 (2), 191-197
- https://doi.org/10.1123/japa.2018-0093
Abstract
Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.Keywords
This publication has 37 references indexed in Scilit:
- Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin ResponsesDiabetes Care, 2012
- Ambulatory Activity of Older Adults Hospitalized with Acute Medical IllnessJournal of the American Geriatrics Society, 2010
- Resistance exercise and appropriate nutrition to counteract muscle wasting and promote muscle hypertrophyCurrent Opinion in Clinical Nutrition and Metabolic Care, 2010
- Skeletal muscle loss: cachexia, sarcopenia, and inactivityThe American Journal of Clinical Nutrition, 2010
- Exercise and Physical Activity for Older AdultsMedicine & Science in Sports & Exercise, 2009
- Artificial gravity maintains skeletal muscle protein synthesis during 21 days of simulated microgravityJournal of Applied Physiology, 2009
- Breaks in Sedentary TimeDiabetes Care, 2008
- Resistance Exercise Reverses Aging in Human Skeletal MusclePLOS ONE, 2007
- Resistance training, insulin sensitivity and muscle function in the elderlyEssays in Biochemistry, 2006
- A Randomized Trial of Care in a Hospital Medical Unit Especially Designed to Improve the Functional Outcomes of Acutely Ill Older PatientsThe New England Journal of Medicine, 1995