Pre-mRNA splicing in the new millennium
- 4 June 2001
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Cell Biology
- Vol. 13 (3), 302-309
- https://doi.org/10.1016/s0955-0674(00)00212-x
Abstract
The past year has witnessed refinements in models of spliceosome assembly pathways and in the understanding of how splicing factors of the serine/arginine-rich (SR) protein family function. The role of splicing in human genetic diseases has also received a lot of attention recently as exonic splicing enhancers become better understood.Keywords
This publication has 54 references indexed in Scilit:
- An Upstream AG Determines Whether a Downstream AG Is Selected during Catalytic Step II of SplicingMolecular and Cellular Biology, 2001
- The Sequence of the Human GenomeScience, 2001
- Initial sequencing and analysis of the human genomeNature, 2001
- Selection of Alternative 5′ Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1Molecular and Cellular Biology, 2000
- Pre-Messenger RNA Processing Factors in the Drosophila GenomeThe Journal of cell biology, 2000
- A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicingProceedings of the National Academy of Sciences of the United States of America, 2000
- Like Attracts Like: Getting RNA Processing Together in the NucleusScience, 2000
- A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicingThe EMBO Journal, 2000
- The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing RegulationThe Journal of cell biology, 2000
- Splicing Defects in the Ataxia-Telangiectasia Gene, ATM: Underlying Mutations and ConsequencesAmerican Journal of Human Genetics, 1999