The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
- 8 April 2010
- journal article
- review article
- Published by Elsevier BV in Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Vol. 1797 (6-7), 1225-1230
- https://doi.org/10.1016/j.bbabio.2010.03.025
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (R01CA08018, R01CA010951, R01CA116257)
This publication has 58 references indexed in Scilit:
- Understanding the Warburg Effect: The Metabolic Requirements of Cell ProliferationScience, 2009
- Bicarbonate Increases Tumor pH and Inhibits Spontaneous MetastasesCancer Research, 2009
- Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapySeminars in Cancer Biology, 2008
- Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancerBritish Journal of Cancer, 2008
- Cancer Cell Metabolism: Warburg and BeyondCell, 2008
- Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesisProceedings of the National Academy of Sciences of the United States of America, 2007
- Lactate and malignant tumors: A therapeutic target at the end stage of glycolysisJournal of Bioenergetics and Biomembranes, 2007
- METABOLIC REMODELING OF MALIGNANT GLIOMAS FOR ENHANCED SENSITIZATION DURING RADIOTHERAPYNeurosurgery, 2006
- Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondriaOncogene, 2006
- On the Origin of Cancer CellsScience, 1956