Incidence, Prevalence, and Management of Intraductal Papillary Mucinous Neoplasm in Olmsted County, Minnesota, 1984-2005
- 1 August 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Pancreas
- Vol. 37 (2), 139-144
- https://doi.org/10.1097/mpa.0b013e318162a10f
Abstract
Intraductal mucinous papillary neoplasm (IPMN) is being recognized with increasing frequency around the world. The true incidence, however, remains unknown. Our goal was to determine the incidence of IPMN in a population study. We used the records-linkage system of the Rochester Epidemiology Project to ascertain age- and sex-adjusted incidence rates of IPMN in Olmsted County, Minn, from January 1, 1984, to December 31, 2005. We also evaluated the number of prevalent cases as of December 31, 2005. We identified 28 incident cases of IPMN. The age- and sex-adjusted cumulative incidence for IPMN in Olmsted County is 2.04 cases per 100,000 persons (95% confidence interval [CI], 1.28-2.80) from 1984 to 2005. Point prevalence on December 31, 2005, was 25.96 cases per 100,000 persons (95% CI, 14.53-37.38 cases) or 1 per 3852. Restricting to county residents 60 years and older, the point prevalence is 99.10 cases per 100,000 persons (95% CI, 54.40-143.79 cases) or one per 1009 persons. Thirty-two percent of patients were treated surgically. The 5-year survival rate after diagnosis was 59.6%. The incidence of IPMN in Olmsted County is low but increasing. Most patients do not die of complications related to the disease.Keywords
This publication has 16 references indexed in Scilit:
- One Thousand Consecutive PancreaticoduodenectomiesAnnals of Surgery, 2006
- Patients with pancreatic intraductal papillary mucinous neoplasms are at high risk of colorectal cancer developmentSurgery, 2006
- International Consensus Guidelines for Management of Intraductal Papillary Mucinous Neoplasms and Mucinous Cystic Neoplasms of the PancreasPancreatology, 2006
- Histopathological Diagnosis of Pancreatic Intraepithelial Neoplasia and Intraductal Papillary-Mucinous Neoplasms: Interobserver AgreementPancreas, 2005
- Outcomes following resection of invasive and noninvasive intraductal papillary mucinous neoplasms of the pancreasThe American Journal of Surgery, 2005
- IPMN: not a new kid on the block anymore.Gastroenterology, 2004
- Intraductal Papillary Mucinous Neoplasms of the PancreasAnnals of Surgery, 2004
- Intraductal Papillary Mucinous Neoplasm: Did it exist prior to 1980?Pancreas, 2003
- Mucin-Producing Neoplasms of the PancreasAnnals of Surgery, 1996
- Differences between solid and duct-ectatic types of pancreatic ductal carcinomasCancer, 1992