Treatment of Intracranial Ependymoma by Surgery Alone
- 1 July 1998
- journal article
- clinical trial
- Published by S. Karger AG in Pediatric Neurosurgery
- Vol. 29 (1), 40-45
- https://doi.org/10.1159/000028683
Abstract
Objective: This study aimed to determine the safety of deferring radiotherapy in pediatric intracranial ependymoma following a radiographically confirmed gross total resection in patients with localized disease. Methods: Children over age 3 were recruited prospectively from 1990 to 1997, following a surgical impression and radiologic confirmation of a gross total resection of an intracranial ependymoma. Results: 10/32 cases of intracranial ependymomas were both eligible and gave consent. 7 remain free of disease without further intervention. 3 recurred, 2 were salvaged with surgery and radiotherapy, none died. Conclusions: Deferral of radiotherapy following gross total resection alone is a safe option in supratentorial ependymomas. The pattern of recurrence is usually local and patients may be salvaged with additional surgery with or without radiotherapy.Keywords
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