Herpes Simplex Encephalitis Complicated by Cerebral Hemorrhage during Acyclovir Therapy
Open Access
- 1 January 2017
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 56 (2), 225-229
- https://doi.org/10.2169/internalmedicine.56.7386
Abstract
Herpes simplex encephalitis (HSE) can be complicated by adverse events in the acute phase. We herein present the case of a 71-year-old woman with HSE complicated by cerebral hemorrhage. She presented with acute deterioration of consciousness and fever and was diagnosed with HSE based on the detection of herpes simplex virus-1 in the cerebrospinal fluid by a polymerase chain reaction. The cerebral hemorrhage developed during acyclovir therapy; however, its diagnosis was delayed for 2 days. After the conservative treatment of the cerebral hemorrhage, the patient made a near-complete recovery. Cerebral hemorrhage should be considered as an acute-phase complication of HSE.Keywords
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