Malignant glioma: Who benefits from adjuvant chemotherapy?
- 8 October 1998
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 44 (4), 691-695
- https://doi.org/10.1002/ana.410440418
Abstract
We combined two randomized prospective Brain Tumor Study Group data sets to analyze the effects of prognostic factors on survival by treatment group. Adjuvant chemotherapy increased long-term survival regardless of prognostic factors. Pathological review revealed that oligodendrogliomas were overrepresented among long-term survivors independent of therapy. Prognostic factors do not predict benefit from adjuvant nitrosourea in malignant gliomas, and long-term survival with chemotherapy is not explained by oligodendroglial tumors.Keywords
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