Transcription Factors in the Cellular Signaling Network as Prime Targets of Chemopreventive Phytochemicals
Open Access
- 1 January 2004
- journal article
- Published by Korean Cancer Association in Cancer Research and Treatment
- Vol. 36 (5), 275-286
- https://doi.org/10.4143/crt.2004.36.5.275
Abstract
Accumulating evidence from epidemiologic and laboratory studies support an inverse relationship between a regular consumption of fruits and vegetables and the risk of specific cancers. Numerous phytochemicals derived from edible plants have been reported to possess ability to interfere with a specific stage of carcinogenic process. Multiple mechanisms have been proposed to account for the anti-carcinogenic actions of dietary constituents, but more attention has recently focussed on intracellular signaling cascades as common molecular targets of a wide variety of chemopreventive phytochemicals.Keywords
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