Exercise‐Induced Reduction in Obesity and Insulin Resistance in Women: a Randomized Controlled Trial
Open Access
- 1 May 2004
- journal article
- clinical trial
- Published by Wiley in Obesity Research
- Vol. 12 (5), 789-798
- https://doi.org/10.1038/oby.2004.95
Abstract
Objectives: To determine the effects of equivalent diet‐ or exercise‐induced weight loss and exercise without weight loss on subcutaneous fat, visceral fat, and insulin sensitivity in obese women. Research Methods and Procedures: Fifty‐four premenopausal women with abdominal obesity [waist circumference 110.1 ± 5.8 cm (mean ± SD)] (BMI 31.3 ± 2.0 kg/m2) were randomly assigned to one of four groups: diet weight loss (n = 15), exercise weight loss (n = 17), exercise without weight loss (n = 12), and a weight‐stable control group (n = 10). All groups underwent a 14‐week intervention. Results: Body weight decreased by ∼6.5% within both weight loss groups and was unchanged in the exercise without weight loss and control groups. In comparison with controls, cardiorespiratory fitness improved within the exercise groups only (p < 0.01). Reduction in total, abdominal, and abdominal subcutaneous fat within the exercise weight loss group was greater (p < 0.001) than within all other groups. The reduction in total and abdominal fat within the diet weight loss and exercise without weight loss groups was greater than within controls (p < 0.001) but not different from each other (p > 0.05). Visceral fat decreased within all treatment groups (p < 0.008), and these changes were not different from each other. In comparison with the control group, insulin sensitivity improved within the exercise weight loss group alone (p < 0.001). Discussion: Daily exercise without caloric restriction was associated with substantial reductions in total fat, abdominal fat, visceral fat, and insulin resistance in women. Exercise without weight loss was also associated with a substantial reduction in total and abdominal obesity.Keywords
This publication has 29 references indexed in Scilit:
- Effects of the Amount of Exercise on Body Weight, Body Composition, and Measures of Central ObesityArchives of Internal Medicine, 2004
- Body Mass Index, Waist Circumference, and Health RiskArchives of Internal Medicine, 2002
- Reduction in Obesity and Related Comorbid Conditions after Diet-Induced Weight Loss or Exercise-Induced Weight Loss in MenAnnals of Internal Medicine, 2000
- Gender-Related Differences in Counterregulatory Responses to Antecedent Hypoglycemia in Normal HumansJournal of Clinical Endocrinology & Metabolism, 2000
- The Use of Areas Under Curves in Diabetes ResearchDiabetes Care, 1995
- Effects of Physical Training on the Metabolism of Skeletal MuscleDiabetes Care, 1992
- Adrenergic regulation of lipolysis in situ at rest and during exercise.JCI Insight, 1990
- Physical Fitness and All-Cause MortalityJama-Journal Of The American Medical Association, 1989
- The effects of exercise and weight loss on plasma lipids in young obese menMetabolism, 1985