Synthesis and pharmacological activity of dermorphin and its N‐terminal sequences
- 1 May 1982
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 19 (5), 536-542
- https://doi.org/10.1111/j.1399-3011.1982.tb02639.x
Abstract
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (demorphin), an opiate-like peptide, and tri-, tetra-, penta- and hexapeptide-amide analogs, were synthesized by conventional methods in solution, to determine the minimum peptide chain-length, required for analgesic activity.Keywords
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