DNA N-glycosylases and UV repair
- 1 September 1980
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 287 (5779), 203-208
- https://doi.org/10.1038/287203a0
Abstract
Repair of some DNA photoproducts can be mediated by glycosylic bond hydrolysis. Thus, Escherichia coli endonuclease III releases 5,6-hydrated thymines as free bases, while T4 UV endonuclease releases one of two glycosylic bonds holding pyrimidine dimers in DNA. In contrast, uninfected E. coli apparently does not excise pyrimidine dimers via a DNA glycosylase.Keywords
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