Smoking, Alcohol, and Betel Quid and Oral Cancer: A Prospective Cohort Study
Open Access
- 17 March 2011
- journal article
- research article
- Published by Hindawi Limited in Journal of Oncology
- Vol. 2011, 1-5
- https://doi.org/10.1155/2011/525976
Abstract
We aimed to investigate the association between smoking, alcoholic consumption, and betel quid chewing with oral cancer in a prospective manner. All male patients age ≥18 years who visited our clinic received an oral mucosa inspection. Basic data including personal habits were also obtained. A multivariate logistic regression model was utilized to determine relevant risk factors for developing oral cavity cancer. A total of 10,657 participants were enrolled in this study. Abnormal findings were found in 514 participants (4.8%). Three hundred forty-four participants received biopsy, and 230 patients were proven to have oral cancer. The results of multivariate logistic regression found that those who smoked, consumed alcohol, and chewed betel quid on a regular basis were most likely to develop cancer (odds ratio: 46.87, 95% confidence interval: 31.84–69.00). Therefore, habitual cigarette smokers, alcohol consumers, and betel quid chewers have a higher risk of contracting oral cancer and should receive oral screening regularly so potential oral cancer can be detected as early as possible.Keywords
This publication has 18 references indexed in Scilit:
- Current topics in the epidemiology of oral cavity and oropharyngeal cancersHead & Neck, 2007
- Socio-demographic factors in the prognosis of oral cancer patientsOral Oncology, 2006
- Nutritional factors and survival of patients with oral cancerHead & Neck, 2006
- Primary oral cancer in a Turkish population sample: Association with sociodemographic features, smoking, alcohol, diet and dentitionOral Oncology, 2005
- Study of Tobacco Habits and Alterations in Enzymatic Antioxidant System in Oral CancerOncology, 2005
- Trends in incidence and prognosis for head and neck cancer in the United States: A site‐specific analysis of the SEER databaseInternational Journal of Cancer, 2005
- Impact of betel quid, tobacco and alcohol on three-stage disease natural history of oral leukoplakia and cancer: implication for prevention of oral cancerEuropean Journal of Cancer Prevention, 2004
- The role of type of tobacco and type of alcoholic beverage in oral carcinogenesisInternational Journal of Cancer, 2003
- Oral cancer in the UK: to screen or not to screenOral Oncology, 1998
- Epidemiology and prevention of oral cancerOral Oncology, 1997