Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides
- 27 May 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 50 (13), 3004-3014
- https://doi.org/10.1021/jm0700215
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinaseNucleic Acids Research, 2006
- Novel Role of 3-Phosphoglycerate Kinase, a Glycolytic Enzyme, in the Activation of L-Nucleoside Analogs, a New Class of Anticancer and Antiviral AgentsJournal of Biological Chemistry, 2003
- Reaction of human UMP‐CMP kinase with natural and analog substratesEuropean Journal of Biochemistry, 2003
- Stereoisomeric Selectivity of Human Deoxyribonucleoside KinasesBiochemistry, 1999
- Low enantioselectivities of human deoxycytidine kinase and human deoxyguanosine kinase with respect to 2'-deoxyadenosine, 2'-deoxyguanosine and their analogsBiochimie, 1999
- Arrays with Local Centers of Symmetry in Space Groups Pca21 and Pna21Acta crystallographica Section B, Structural science, crystal engineering and materials, 1998
- Chiral Discrimination of 2′-Deoxy-l-cytidine andl-Nucleotides by Mouse Deoxycytidine Kinase: Low Stereospecificities for Substrates and EffectorsBiochemical and Biophysical Research Communications, 1997
- Refinement of Macromolecular Structures by the Maximum-Likelihood MethodActa Crystallographica Section D-Biological Crystallography, 1997
- Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinaseJournal of General Virology, 1991
- Near-coincidence orientations in hexagonal materials: from a unified twin approach to a quasiperiodic descriptionActa Crystallographica Section A Foundations of Crystallography, 1991