A simplified schematic method for deriving steady-state rate equations using a modification of the “theory of graphs” procedure

Abstract

A simple schematic procedure for the derivation of steady-state enzyme rate equations is presented. The method is a modification of an approach described by Volkenstein and Goldstein (1966) based upon the “Theory of Graphs” procedure. The advantage of this method for rate equation derivations is that it requires little algebra and avoids problems of the type encountered in other schematic methods.