Review article Male breast cancer - an andrological disease: risk factors and diagnosis
- 1 December 2004
- journal article
- review article
- Published by Hindawi Limited in Andrologia
- Vol. 36 (6), 346-354
- https://doi.org/10.1111/j.1439-0272.2004.00639.x
Abstract
Gynaecomastia, the enlargement of the male breast, is considered as an andrological disease. To date, a review on male breast cancer (MBC) has not been published in an andrological journal. The papers underlying this review were published from authors of different institutions: Clinical Genetics, Dermatology, Gynaecology, Internal Medicine, Oncology, Pathology, Psychiatry, Radiology and Surgery. MBC accounts for approximately 1% of breast cancer patients. A total of 182 men died of breast cancer in 1999, in Germany. In the US, 1500 new cases per year occur. MBC accounts for <5% of surgically removed breast lumps. Diseases with increased oestrogen action increase the risk of MBC. Mutations of distinct genes are estimated to account for up to roughly 10% of MBC. BRCA1 and BRCA2 gene mutations are responsible for approximately 80% of the families with hereditary breast cancer. The diagnosis of MBC is not possible without histological examination. Different diagnostic procedures such as clinical diagnosis, sonography, mammography, fine-needle biopsy and core needle facilitate the decision whether a biopsy is necessary.Keywords
This publication has 85 references indexed in Scilit:
- Role of CHEK2*1100delC in unselected series of non‐BRCA1/2 male breast cancersInternational Journal of Cancer, 2003
- CHEK2 1100delC is not a risk factor for male breast cancer populationInternational Journal of Cancer, 2003
- Inherited BRCA2 mutations in African Americans with breast and/or ovarian cancer: a study of familial and early onset casesHuman Genetics, 2003
- Risk factors for male breast cancer in Canada, 1994–1998European Journal of Cancer Prevention, 2002
- Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibilityJournal of Medical Genetics, 2002
- Elevated risk for male breast cancer after occupational exposure to gasoline and vehicular combustion productsAmerican Journal of Industrial Medicine, 2000
- Fine Needle Aspiration Cytology in the Management of Male Breast MassesActa Cytologica, 1999
- Risk of endometrial and breast cancer in patients with diabetes mellitusInternational Journal of Cancer, 1997
- Lobular carcinoma of the male breast associated with the use of cimetidineVirchows Archiv A Pathological Anatomy and Histopathology, 1997
- Klinische Relevanz der Mammographie beim MannRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 1996