Gastrin
- 19 June 1975
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 292 (25), 1324-1334
- https://doi.org/10.1056/nejm197506192922505
Abstract
(First of Two Parts)Chemistry and PhysiologyHistoricalWHEN Bayliss and Starling1 discovered secretin in 1902, they quickly saw that they had uncovered not just a new substance but a new concept with broad biologic implications. They regarded secretin as a prototype of an entire system of "chemical messengers" that share with the nervous system the task of co-ordinating the activities of the whole body. Both systems provide mechanisms whereby stimuli received at one part of the body can control the activity of a distant part. In their first paper on secretin, Bayliss and Starling1 suggested gastric secretion as an . . .Keywords
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