Stimulation of glycogenolysis in hepatocytes by angiotensin II may involve both calcium release and calcium influx
- 22 August 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 160 (1-2), 259-263
- https://doi.org/10.1016/0014-5793(83)80978-8
Abstract
The stimulation of [3H]glucose release (a measure of glycogenolysis) from isolated guinea pig hepatocytes by Ca-mobilizing agonists can be resolved into two phases. The initial transient phase is independent of extracellular Ca, and is probably a result of Ca released from an intracellular pool. The second phase occurs only in the presence of extracellular Ca, which suggests that Ca-influx is also involved in the mechanism of Ca-mobilization by these agents in the guinea pig hepatocyte.Keywords
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