Taurolithocholic Acid Exerts Cholestatic Effects via Phosphatidylinositol 3-Kinase-dependent Mechanisms in Perfused Rat Livers and Rat Hepatocyte Couplets
Open Access
- 1 May 2003
- journal article
- Published by Elsevier BV
- Vol. 278 (20), 17810-17818
- https://doi.org/10.1074/jbc.m209898200
Abstract
No abstract availableThis publication has 36 references indexed in Scilit:
- Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C–dependent mechanisms in cholestatic rat liverHepatology, 2001
- Hepatobiliary transportJournal of Hepatology, 2000
- Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytesHepatology, 1999
- Tauroursodeoxycholate and S-adenosyl-L-methionine exert an additive ameliorating effect on taurolithocholate-induced cholestasis: A study in isolated rat hepatocyte coupletsHepatology, 1999
- Molecular Pathogenesis of CholestasisNew England Journal of Medicine, 1998
- Effects of tauroursodeoxycholic acid on cytosolic Ca2+ signals in isolated rat hepatocytesGastroenterology, 1993
- Bile acids mobilise internal Ca2+ independently of external Ca2+ in rat hepatocytesEuropean Journal of Biochemistry, 1990
- Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liverJournal of Hepatology, 1990
- Effect of sodium taurolithocholate on bile flow and bile acid excretionJCI Insight, 1968
- Cholestasis in Rats induced by TaurolithocholateNature, 1966