A Primer on Monkeypox Virus for Obstetrician–Gynecologists
Open Access
- 11 July 2022
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Obstetrics & Gynecology
- Vol. 140 (3), 391-397
- https://doi.org/10.1097/aog.0000000000004909
Abstract
Since May 2022, more than 6,900 cases of monkeypox virus infection have been reported in 52 countries. The World Health Organization is planning to rename the virus and its clades to reduce stigma. As of July 5, 2022, 556 cases have been reported in 33 U.S. states and the District of Columbia. The initial cases were travel-associated; however, person-to-person transmission is now occurring domestically. Close, sustained skin-to-skin contact, including during sexual activity, appears to be the primary mode of transmission. The risk of widespread community transmission remains low; however, rapid identification of monkeypox virus infection and isolation of affected individuals is critical to prevent further transmission. Most but not all cases have occurred in males; some infections have started with anogenital lesions and can be mistaken for common sexually transmitted infections. To facilitate rapid, accurate diagnosis of monkeypox virus infection, obstetrician–gynecologists (ob-gyns) in the United States should ask about recent travel history and new ulcers or lesions and perform a thorough visual inspection of skin and mucosal sites (oral, genital, perianal area) in patients presenting with new rash. Obstetrician–gynecologists should become familiar with the appearance of monkeypox lesions and know whom to call to report a suspected case, how and when to test for monkeypox virus, and how to counsel patients. In the event of a suspected case, ob-gyns should follow infection-control guidelines to prevent transmission and make recommendations to prevent further community spread. This article outlines the diagnosis, prevention, and treatment of monkeypox virus infection, monkeypox virus infection during pregnancy, and implications for practicing ob-gyns in the United States.Keywords
This publication has 11 references indexed in Scilit:
- Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022Morbidity and Mortality Weekly Report (MMWR), 2022
- Monkeypox in a Traveler Returning from Nigeria — Dallas, Texas, July 2021Morbidity and Mortality Weekly Report (MMWR), 2022
- Fatal Cowpox Virus Infection in Human Fetus, France, 2017Emerging Infectious Diseases, 2021
- A Preparedness Model for Mother–Baby Linked Longitudinal Surveillance for Emerging ThreatsMaternal and Child Health Journal, 2021
- Human-to-Human Transmission of Monkeypox Virus, United Kingdom, October 2018Emerging Infectious Diseases, 2020
- Vaccinating against monkeypox in the Democratic Republic of the CongoAntiviral Research, 2018
- Maternal and Fetal Outcomes Among Pregnant Women With Human Monkeypox Infection in the Democratic Republic of CongoThe Journal of Infectious Diseases, 2017
- The Role of the Obstetrician–Gynecologist in Emerging Infectious Diseases: Monkeypox and PregnancyObstetrics & Gynecology, 2004
- Smallpox and pregnancy: from eradicated disease to bioterrorist threatObstetrics & Gynecology, 2002
- Virus infections (other than rubella) during pregnancy.BMJ, 1979