The Solved and Unsolved Mysteries of the Genetics of Early-Onset Alzheimer 's Disease
- 1 January 2002
- journal article
- review article
- Published by Springer Science and Business Media LLC in NeuroMolecular Medicine
- Vol. 2 (1), 01-10
- https://doi.org/10.1385/nmm:2:1:01
Abstract
No abstract availableKeywords
This publication has 68 references indexed in Scilit:
- A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and NotchNeurobiology of Disease, 2002
- The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formationNature Neuroscience, 2001
- A Pathogenic Presenilin-1 Deletion Causes Abberrant Aβ42 Production in the Absence of Congophilic Amyloid PlaquesPublished by Elsevier BV ,2001
- Identification of a novel 4.6-kb genomic deletion in presenilin-1 gene which results in exclusion of exon 9 in a Finnish early onset Alzheimer's disease family: an Alu core sequence-stimulated recombination?European Journal of Human Genetics, 2000
- Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expressionHuman Molecular Genetics, 2000
- Tau is a candidate gene for chromosome 17 frontotemporal dementiaAnnals of Neurology, 1998
- Wide range in age of onset for chromosome 1‐related familial Alzheimer's diseaseAnnals of Neurology, 1996
- Alzheimer's Disease and Possible Gene InteractionScience, 1994
- Alzheimer's Disease: The Amyloid Cascade HypothesisScience, 1992
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's diseaseNature, 1991