Overexpression of the Response Regulator evgA of the Two-Component Signal Transduction System Modulates Multidrug Resistance Conferred by Multidrug Resistance Transporters
Open Access
- 15 February 2001
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 183 (4), 1455-1458
- https://doi.org/10.1128/jb.183.4.1455-1458.2001
Abstract
Overexpression of evgA , a response regulator of a two-component system, increased multidrug efflux in Escherichia coli . Since overexpression of the emrKY operon, which is controlled by evgAS , could account only for deoxycholate resistance, the evgAS locus apparently controls expression of at least one other multidrug efflux operon.Keywords
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