A Self-Managed System for Automated Assessment of UPDRS Upper Limb Tasks in Parkinson’s Disease
Open Access
- 18 October 2018
- Vol. 18 (10), 3523
- https://doi.org/10.3390/s18103523
Abstract
A home-based, reliable, objective and automated assessment of motor performance of patients affected by Parkinson’s Disease (PD) is important in disease management, both to monitor therapy efficacy and to reduce costs and discomforts. In this context, we have developed a self-managed system for the automated assessment of the PD upper limb motor tasks as specified by the Unified Parkinson’s Disease Rating Scale (UPDRS). The system is built around a Human Computer Interface (HCI) based on an optical RGB-Depth device and a replicable software. The HCI accuracy and reliability of the hand tracking compares favorably against consumer hand tracking devices as verified by an optoelectronic system as reference. The interface allows gestural interactions with visual feedback, providing a system management suitable for motor impaired users. The system software characterizes hand movements by kinematic parameters of their trajectories. The correlation between selected parameters and clinical UPDRS scores of patient performance is used to assess new task instances by a machine learning approach based on supervised classifiers. The classifiers have been trained by an experimental campaign on cohorts of PD patients. Experimental results show that automated assessments of the system replicate clinical ones, demonstrating its effectiveness in home monitoring of PD.Keywords
This publication has 33 references indexed in Scilit:
- Analysis of the Accuracy and Robustness of the Leap Motion ControllerSensors, 2013
- Finger Tapping Clinimetric Score Prediction in Parkinson's Disease Using Low-Cost AccelerometersComputational Intelligence and Neuroscience, 2013
- Assessing Bradykinesia in Parkinsonian DisordersFrontiers in Neurology, 2013
- Feasibility of home-based automated Parkinson's disease motor assessmentJournal of Neuroscience Methods, 2012
- Design and evaluation of a low-cost instrumented glove for hand function assessmentJournal of NeuroEngineering and Rehabilitation, 2012
- Differential response of speed, amplitude, and rhythm to dopaminergic medications in Parkinson's diseaseMovement Disorders, 2011
- The modified bradykinesia rating scale for Parkinson's disease: Reliability and comparison with kinematic measuresMovement Disorders, 2011
- LIBSVMACM Transactions on Intelligent Systems and Technology, 2011
- Regularization and Variable Selection Via the Elastic NetJournal of the Royal Statistical Society Series B: Statistical Methodology, 2005
- An overview of statistical learning theoryIEEE Transactions on Neural Networks, 1999