Risk Factors for Carotid Atherosclerosis: The Kuopio Ischaemic Heart Disease Risk Factor Study
- 1 January 1989
- journal article
- Published by Informa UK Limited in Annals of Medicine
- Vol. 21 (3), 227-229
- https://doi.org/10.3109/07853898909149939
Abstract
We assessed the severity of carotid atherosclerosis in 412 men from eastern Finland aged 42, 48, 54 or 60 years at examination with B-mode ultrasonography in 1987 in the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD). Thirty-seven per cent of participants had intimal-medial thickening, 10% had plaques and 2% had stenosis. Age (P>0.001), cigarette-years (P>0.001), serum LDL cholesterol (P = 0.005), low income (P = 0.020) and low alcohol consumption (P = 0.048) had significant partial associations with the severity of carotid atherosclerosis. A linear regression model including these variables and plasma fibrinogen (NS) and serum HDL-cholesterol (NS) accounted for 33% of the variation in atherosclerosis severity. Our data provide further evidence on the role of smoking and LDL-cholesterol in atherosclerosis.Keywords
This publication has 5 references indexed in Scilit:
- Prevalence of carotid atherosclerosis and serum cholesterol levels in eastern Finland.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1988
- Ultrasound in the study of atherosclerosisJapanese Journal of Clinical Oncology, 1986
- Noninvasive assessment of atherosclerosisProgress in Cardiovascular Diseases, 1984
- Ultrasonic tissue characterization of atheromatous plaques using a high resolution real time scannerJapanese Journal of Clinical Oncology, 1983
- Lipoprotein fractionation.Journal of Clinical Pathology, 1973