Evidence for a Vesicular Transport Mechanism in Hepatocytes for Biliary Secretion of Immunoglobulin A
- 13 June 1980
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 208 (4449), 1276-1278
- https://doi.org/10.1126/science.7375938
Abstract
Quantitative electron microscopic autoradiography and diaminobenzidine cytochemistry provide evidence for an uptake and vesicular transport mechanism for iodine-125-labeled immunoglobulin A from plasma to bile by hepatocytes in vivo. The data confirm the existence of a hepatobiliary pathway for secretion of immunoglobulin A into the intestine and are consistent with a vesicular transport mechanism for biliary proteins within liver parenchymal cells.Keywords
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