Impact of long-term treatment of onchocerciasis with ivermectin in Kaduna State, Nigeria: first evidence of the potential for elimination in the operational area of the African Programme for Onchocerciasis Control
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Open Access
- 7 February 2012
- journal article
- Published by Springer Science and Business Media LLC in Parasites & Vectors
- Vol. 5 (1), 28-9
- https://doi.org/10.1186/1756-3305-5-28
Abstract
Onchocerciasis can be effectively controlled as a public health problem by annual mass drug administration of ivermectin, but it was not known if ivermectin treatment in the long term would be able to achieve elimination of onchocerciasis infection and interruption of transmission in endemic areas in Africa. A recent study in Mali and Senegal has provided the first evidence of elimination after 15-17 years of treatment. Following this finding, the African Programme for Onchocerciasis Control (APOC) has started a systematic evaluation of the long-term impact of ivermectin treatment projects and the feasibility of elimination in APOC supported countries. This paper reports the first results for two onchocerciasis foci in Kaduna, Nigeria.Keywords
This publication has 26 references indexed in Scilit:
- Onchocerciasis in the Americas: from arrival to (near) eliminationParasites & Vectors, 2011
- Compliance with eight years of annual ivermectin treatment of onchocerciasis in Cameroon and NigeriaParasites & Vectors, 2011
- Feasibility of Onchocerciasis Elimination with Ivermectin Treatment in Endemic Foci in Africa: First Evidence from Studies in Mali and SenegalPLoS Neglected Tropical Diseases, 2009
- The Mectizan Donation Program: 20 years of successful collaboration — a retrospectivePathogens and Global Health, 2008
- The impact of ivermectin treatment alone and when in parallel with Simulium neavei elimination on onchocerciasis in UgandaTropical Medicine & International Health, 2004
- Eliminating Onchocerciasis after 14 Years of Vector Control: A Proved StrategyThe Journal of Infectious Diseases, 2001
- Distribution and aetiology of blindness and visual impairment in mesoendemic onchocercal communities, Kaduna State, Nigeria. Kaduna Collaboration for Research on Onchocerciasis.British Journal of Ophthalmology, 1994
- Reduction in incidence of optic nerve disease with annual ivermectin to control onchocerciasisThe Lancet, 1993
- Onchocerciasis control by large-scale ivermectin treatmentThe Lancet, 1991
- The reproductive lifespan of Onchocerca volvulus in West African savannaActa Tropica, 1991