Pleuropulmonary Disease in a Man with Diabetes Who Was Treated with Troglitazone

Abstract

Troglitazone is an antidiabetic drug that decreases hyperglycemia by increasing the sensitivity of peripheral tissue to insulin.¹ Its most serious adverse effect is hepatic dysfunction, which occurs in a small percentage of patients.² We describe a case of pleuritis in a patient who was treated with troglitazone.