A component of green tea, (−)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins
- 1 March 2007
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 354 (4), 852-857
- https://doi.org/10.1016/j.bbrc.2007.01.003
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Role of PI3‐kinase/Akt signalling pathway in renal function and cell proliferation after renal ischaemia/reperfusion injury in miceNephrology, 2006
- Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by AktOncogene, 2004
- Anti-HLA class I antibody–mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cellsHuman Immunology, 2004
- Epigallocatechin-3-gallate Inhibits Epidermal Growth Factor Receptor Signaling PathwayJournal of Biological Chemistry, 2004
- Modulation of phosphatidylinositol‐3‐kinase/protein kinase B‐ and mitogen‐activated protein kinase‐pathways by tea polyphenols in human prostate cancer cellsJournal of Cellular Biochemistry, 2003
- Inhibition of Carcinogenesis by TeaAnnual Review of Pharmacology and Toxicology, 2002
- MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cellsOncogene, 2000
- A specific function for phosphatidylinositol 3-kinase α (p85α-p110α) in cell survival and for phosphatidylinositol 3-kinase β (p85α-p110β) in de novo DNA synthesis of human colon carcinoma cellsOncogene, 2000
- Reduced Risk of Esophageal Cancer Associated With Green Tea ConsumptionJNCI Journal of the National Cancer Institute, 1994
- Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell deathCell, 1993