IL-9 in Allergic Inflammation
- 1 May 2004
- journal article
- review article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 134 (1), 79-87
- https://doi.org/10.1159/000078384
Abstract
Th2 type cytokines such as interleukin (IL)-4, IL-5, IL-9, and IL-13 are important mediators in allergic inflammation. The present review will focus on the role of IL-9 in allergic inflammation. The structure and genomic architecture of IL-9 and its receptor, the source of IL-9 and its regulation as well as its effects on different cell types will be reviewed. Furthermore, the specific role of IL-9 in allergic diseases and the potential therapeutic approach of blocking IL-9 will be discussed.Keywords
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