Knowledge of developmental pharmacology and modeling approaches should be used to avoid useless trials in children
Open Access
- 25 April 2009
- journal article
- Published by Springer Science and Business Media LLC in European Journal of Clinical Pharmacology
- Vol. 65 (8), 849-850
- https://doi.org/10.1007/s00228-009-0655-2
Abstract
No abstract availableKeywords
This publication has 5 references indexed in Scilit:
- Tailor-made drug treatment for children: Creation of an infrastructure for data-sharing and population PK–PD modelingDrug Discovery Today, 2009
- Off-label use of medicines in children: can available evidence avoid useless paediatric trials?European Journal of Clinical Pharmacology, 2008
- Considerations in the Rational Design and Conduct of Phase I/II Pediatric Clinical Trials: Avoiding the Problems and PitfallsClinical Pharmacology & Therapeutics, 2007
- The Trial of Infant Response to DiphenhydramineArchives of Pediatrics & Adolescent Medicine, 2006
- Diphenhydramine: Pharmacokinetics and Pharmacodynamics in Elderly Adults, Young Adults, and ChildrenThe Journal of Clinical Pharmacology, 1990